Kevin Xu
Founder of AfterHour, CEO of Alpha
A leadership change at the FDA could favor Hims & Hers, since Commissioner Marty Makary was known for targeting its compounded GLP-1 pill. Per CBS, President Trump has approved a plan to fire Makary. It is not yet official, which is why the stock hasn't moved sharply; once it is, a sharp move may follow. x.comÂ
Peptides could fast-track Hims & Hers' patient network like Harry Potter did for Amazon. Its US-based supply chain, manufacturing and clinical network could serve new demand. The FDA's interim compounding policy cleared White House review and may be released any day, potentially allowing certain peptides; Lee Rosebush says six are in Category 1. The policy's terms remain unknown. x.com x.com x.com x.comÂ
RFK Jr.'s health department's notice that the FDA will not take action against pharmacies compounding six unapproved peptides brings Hims & Hers' peptide opportunity forward. Pharmacies can offer BPC-157, TB-500, epitalon, KPV, MOTS-c and semax now while a formal rule change is worked on. This is the most bullish news for Hims & Hers. x.comÂ
Hims & Hers faces mounting headwinds from an FTC lawsuit and a setback to its peptide expansion. The FTC alleges deceptive subscription practices and improper sharing of sensitive health data with ad platforms. An FDA advisory panel also voted against adding emideltide to the 503A Bulks List, a blow to Hims' peptide and compounding plans. x.comÂ
Hims & Hers could gain a massive new growth opportunity if peptide access expands after the White House completed its review of the FDA's interim policy. Six peptides, including BPC-157, TB-500 and MOTS-c, could gain expanded access; Hims is preparing treatments. The potential market is $2B-$3B. x.comÂ
Hims & Hers' peptide capabilities may be underappreciated, setting up a strong bounce after peptide news. Per @riyadosofian, it is the only telehealth company with a peptide facility and global distribution system. A strong bounce is expected now as the stock holds outside its wedge. x.com x.comÂ
Hims & Hers is getting hit by Amazon, a competitor using its own generic product to undercut the Hims generic offering. x.comÂ
Hims & Hers may benefit as GLP-1 drugmakers lose pricing power. With dozens of GLP-1s in development on top of those available today, no pharmaceutical company appears to have sustainable pricing power, which looks good for Hims & Hers. x.comÂ
A draft HHS policy opening a regulated path for peptides advances Hims & Hers' peptide opportunity. CEO Andrew Dudum says its planned Peptides+ rollout would use clinician-led protocols and a fully US-based manufacturing and supply chain; the policy is still a draft. x.comÂ
Hims & Hers looks bearish on news that Chinese producers are moving into bootleg peptides sold in the US. Per a WSJ report shared by @tradfi, Chinese fentanyl precursor producers are pivoting to selling bootleg peptides in the US, and several Chinese peptide vendors were previously indicted in the US over the fentanyl trade. x.comÂ
Hims & Hers' newly previewed Peptides+ offering could add a growth vertical to its healthcare platform. Management plans access to sermorelin, glutathione and NAD+; recent regulatory developments may also open a path for BPC-157 and TB-500, subject to further conditions. Rollout and commercial opportunity remain unproven, and margins and execution are still risks. x.comÂ
