Dr J Rould
Full-Time Tech Investor, Quantum/Cybersecurity, Philosophy Background
AbCellera's new collaboration with Vertex, which uses AbCellera's platform while footing the bill, is a welcome sign. Smaller-cap players like AbCellera are more interesting than Vertex, which has been a 50-bagger over 20 years and is now a $137B giant whose best gains have already happened. x.comÂ
AbCellera Biologics is a high-risk moonshot with an interesting setup as its pipeline moves into the clinic. 2025 revenue rose to $75.1M from $28.8M, the net loss narrowed, and it ended the year with about $561M in cash and securities plus roughly $135M of non-dilutive government funding. It advanced two programs into clinical trials, two more into IND/CTA-enabling work, and has 19 partner molecules in the clinic. x.comÂ
AbCellera remains considerably undervalued even at UBS's $18 target because that figure accounts for ABCL635 alone, not the rest of the pipeline. UBS initiated coverage with a Buy rating, but one price increase at a time. x.com x.comÂ
AbCellera's premium valuation looks risky given its slow revenue growth and a 24% short float. x.comÂ
AbCellera's $200M offering looks bullish, because dilution is not always negative when it pulls revenue forward or is accretive long term. As @JackPrescottX notes, the company already had $675M of available liquidity, and the raise suggests it plans to take ABCL635 all the way to market rather than partner it. Any extended dip is a buying opportunity. x.comÂ
AbCellera's excellent Phase 2 data validates AI-augmented antibody discovery and commercialization as the future of medicine. Any large pullback would be a chance to add. x.com x.comÂ
AbCellera may be totally disrupted by LigandForge, which first looked like it could be the catalyst for the company. x.com x.comÂ
AbCellera is being re-rated from a contract research vendor into a co-development asset owner. Its Jazz Pharmaceuticals deal to co-develop T-cell engagers for GI and solid tumors lifts fair value over 20%, per several analysts. Interim Phase 1 data for ABCL635, for menopausal hot flashes, showed strong safety, no liver toxicity and monthly dosing potential. It has 14 clinical molecules and 40 partner programs, and $655M of liquidity, including government funding, all but removes bankruptcy risk. … Show more
AbCellera Biologics is breaking through its September value area as call flow picks up, putting the upside volume point of control in view as a target. x.comÂ
AbCellera looks deeply undervalued against private AI drug-discovery valuations. It is worth about $4B in public markets, while DeepMind spinout Isomorphic Labs is reportedly seeking a valuation of $40B or more in private markets. x.comÂ
AbCellera is an elite generator of drug call options, and ABCL635 just delivered. The company reported positive top-line Phase 2 results showing significant reductions in the frequency and severity of vasomotor symptoms with a favorable tolerability profile. The stock has gone up and down, but the core idea of proven antibody drug discovery with asymmetric upside remains. x.com x.comÂ