Ross Gerber
CEO of Gerber Kawasaki, Portfolio Manager of GK ETF
Eli Lilly is one of the most incredible opportunities in the market because its dominance in weight loss and the dramatic health benefits of GLP-1 drugs are underappreciated relative to America's obesity. Obesity is crushing the healthcare system, the drugs work and people should take them. Lilly is the king of GLP-1s, retatrutide should be huge, and owning Novo Nordisk alongside it is not needed. x.com x.com x.com x.com x.comÂ
Eli Lilly's broader biology opportunity leaves far more upside than most appreciate. Q3 earnings crushed estimates as expected: revenue was $24.4B versus $22.6B expected, and adjusted EPS was $7.48 versus $6.50. GLP-1s fund its longer-term drug-discovery platform rather than defining the whole thesis. x.comÂ
Eli Lilly's GLP-1 and metabolic franchise can compound demand and cash flows while rate fears punish leveraged AI stories. It is preferable as a defensive-growth holding into its October 29 earnings over chasing a chip bounce. Continued healthcare volume leadership would support the sleeve; if semiconductors reclaim leadership first, the rotation is already crowded the other way. x.com x.comÂ
Eli Lilly is too expensive a stock to be interesting, and its oral pill Foundayo is not serious competition for Novo Nordisk's oral Wegovy. A post the author quotes calls the launch a disaster: Lilly still hasn't given prescription figures three weeks in, as Novo did in January, and 35% of volume coming from telehealth suggests Lilly Direct is not performing well. x.comÂ
Eli Lilly can reinvest its GLP-1 cash flow into biological intelligence, building on the growth of its metabolic drugs. AI agent swarms working on scientific problems underpin the view that Lilly is becoming the world's most important AI company and could be the largest US company by decade's end. 2027 will be a year of cures and AI-driven scientific breakthroughs. x.comÂ
GLP-1 drugs are a secular shift in healthcare spending, and Eli Lilly is leading it. Q1 revenue rose 56% to $19.8B, with Mounjaro up 125% to $8.66B and Zepbound up 80% to $4.16B, and full-year guidance was raised to $82-85B. GLP-1 patients are expected to grow from 20 million to 30 million globally by year-end, and FDA approval of the oral GLP-1 orforglipron expands the addressable market further. x.comÂ
Eli Lilly is overvalued and needs to pull back, since a 40 P/E is high for any biotech or healthcare stock, which keeps Novo Nordisk the better side of the pair. A post the author replies to calls Novo an excellent entry today but doubts shorting Lilly given how much it has going on. x.comÂ
Eli Lilly's Foundayo demand looks stronger than its Q3 sales miss implies. The miss looks like timing and inventory, not weak demand: the pill now has about 40% of new US oral GLP-1 prescriptions, roughly double last quarter. Lilly has 63% of the US GLP-1 market; new overseas pill launches could add another leg next quarter. Foundayo could eventually outsell both Mounjaro and Zepbound. GLP-1 revenue funds Lilly's AI drug-discovery ambitions. x.comÂ
Eli Lilly's retatrutide should accelerate adoption because it raises calorie burn rather than merely suppressing appetite, a bigger leap than the previous generational change. Visible results could turn users into walking advertisements and create peer pressure. Lilly will probably become at least a $5 trillion company in the coming years, roughly 5x with a near-straight-line climb, on a projection of as many as a billion users. x.comÂ
Eli Lilly looks expensive at 26x forward earnings when drugmakers usually get 20x. Fair value is about $820.69-$1,045, or 20x next year's $46.63 EPS give or take 12%, so the $1,215 price sits 16% above the top of that range. The valuation also leans on forecasts, with forward earnings 55% above trailing. This is a valuation-level read only, not fundamental work. x.comÂ
Eli Lilly should see further positive revenue revisions as it expands the weight-loss market by reducing gastrointestinal side effects and lowering treatment costs. Strong demand for Mounjaro and Zepbound drove a second FY2026 revenue guidance raise in three months, to $91B-$92B from $85B-$87B. Lilly Direct and the Medicare Bridge program for seniors aim to make treatment cheaper. At 29x 2027 earnings against 15% revenue and 20% EPS growth projected for 2027-30, Lilly still looks cheap. x.comÂ