Eli Lilly's retatrutide posted very impressive Phase 3 results and could become the best-selling drug ever if it preserves muscle better than rivals. At 80 weeks, patients on 4mg, 9mg and 12mg lost 19.0%, 25.9% and 28.3% of body weight, and 27.9-30.3% at 104 weeks; 62.5% on 12mg lost over 25%. As a triple agonist it can deliver better results at lower doses than semaglutide and tirzepatide, with better visceral fat, cholesterol and blood sugar markers. Muscle-preservation data isn't in yet. x.com x.com x.comÂ
