Tempus AI may be about to go on a run, and its short interest looks a bit rich. As of June 15, 38M of its 180M shares outstanding were sold short, a roughly $2B position at $54. x.comÂ
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Equity Investor, Biotech & Software Focus
Tempus AI is next among biotechs to receive AI capex, since everyone will want access to its data. Per @byobio, frontier labs engaging pharma will find only about a dozen diagnostic companies have multimodal molecular, imaging and clinical data at scale, and Tempus has applied AI to data from the start. Twist Bioscience rose about 200% once its AI story became consensus. x.com x.comÂ
Tempus AI's 31% short interest adds fuel to its Stage 2 breakout. x.comÂ
Tempus AI's selloff after it beat and raised guidance looks like a great deal, and a further drop would be a chance to buy more. x.comÂ
Tempus AI is a short idea because the stock is being pumped on recent FDA clearances for its EKG-AI tools, while the revenue from them is far off and may never materialize. x.comÂ
Tempus AI is being repriced because its acquisition of Personalis benefits directly from positive Moderna news, while short covering is still underway. Short interest is about 30 million shares, over eight days of normal 3-5 million share volume, and the three-day surge absorbed under a third of it. A small market cap makes the stock easy to push higher, and bullish divergences on the three-day and weekly charts usually last weeks to months. Resistance sits at 74-76, 80 and 84-86. x.com x.com … Show more
Hims & Hers' compounding direct-to-consumer distribution makes it stupidly undervalued next to Tempus AI. Hims has $2.6B in trailing revenue at a $6.7B market cap, with 66.5% annual revenue growth from Q3 2021 to Q2 2026; Tempus has $1.4B in revenue, a $14.9B market cap and 40.4% annual growth. x.comÂ
Tempus AI is a second- or third-tier genomic lab whose AI story is marketing mumbo jumbo, and its management team are promoters. x.comÂ
Tempus AI is one of the highest-conviction setups now, and the widespread doubt about its move is itself bullish. The skepticism was earned by a year of false starts, but clearing $58 should flip sentiment quickly, with a near-term target of $68-$73. A weekly break above $73 sets a medium- to long-term target of $144-$168. Momentum is building on both lower and higher timeframes, while about 38M shares, roughly 28% of the float, are sold short into the breakout. x.com x.com x.comÂ
Tempus AI is still undervalued because its data business alone may be worth a large share of the company. Data and Applications revenue of about $400 million in FY26, growing at management's roughly 30% long-term rate, reaches about $676 million by FY28; at a conservative 12-14x sales that is $8.1-9.5 billion. That leaves the diagnostics business, with about $1.2 billion of revenue, valued at only about $4.5 billion. x.comÂ
Tempus AI may go lower near term because of valuation, leadership reputation and insider selling, despite an amazing business. With about 25% growth expected and profitability uncertain, it is not obviously cheap. Glassdoor reviews matter in medicine's high-trust setting, and ongoing insider sales echo founder patterns that ended badly. The data piece, about 5% of market cap, can earn a high multiple, so the stock looks reasonably priced if adoption continues. x.comÂ
Tempus AI's $1.5B all-stock acquisition of Personalis is smart long-term positioning despite the dilution-driven dip. Owning Personalis's NeXT Personal MRD technology outright lets Tempus pair liquid-biopsy recurrence testing, one of oncology's fastest-growing areas, with its multimodal dataset and AI at scale. That extends Tempus from diagnostics into high-margin longitudinal monitoring and could strengthen its moat, though execution will decide it. x.comÂ