Eli Lilly's broader biology opportunity leaves far more upside than most appreciate. Q3 earnings crushed estimates as expected: revenue was $24.4B versus $22.6B expected, and adjusted EPS was $7.48 versus $6.50. GLP-1s fund its longer-term drug-discovery platform rather than defining the whole thesis. x.com 

Hims & Hers suffers from bad management, and government pressure is squeezing its pharma margins. x.com 

Hims & Hers' distribution case is stronger because Novo Nordisk chose to sell through it after suing it. Nearly 2.9 million subscribers spend $92 monthly on average, up 21%, as customers add products. The base case is $117-$156 by 2030. Branded weight-loss drugs broke margin expansion for a year, maybe more. FTC cancellation claims pose a retention risk, though growth does not suggest trapped customers. Subscriber growth stalling or retention built on friction would prompt a sale. x.com 

Novo Nordisk's management showed too little action against near-term problems, leaving the case in real doubt for the first time. A 5-10-year recovery plan clashes with the semaglutide patent expiring within that window, already lost in Canada, India and Turkey, while Eli Lilly poses real threats. Pipeline work in blood/endocrine, liver and cardiovascular is exciting and diversifying would be a game changer, and NovoCare is a positive, but the clock is running and management is uninspiring. … Show more

Hims & Hers looks good on paper, but past revenue growth does not guarantee future growth and margins are falling, which is very bad. Its peptides story could rerate the stock if executed, but it brings another regulatory overhang: peptides will be in regulation headlines every day and the stock will trade on them. x.com 

Hims & Hers may benefit as GLP-1 drugmakers lose pricing power. With dozens of GLP-1s in development on top of those available today, no pharmaceutical company appears to have sustainable pricing power, which looks good for Hims & Hers. x.com 

Hims & Hers faces continued selling pressure as GLP-1 competition intensifies. Q1 revenue of $608.1 million missed the $617.5 million estimate, gross margin was 65.0% versus 71.7% expected, and EPS turned negative for the first time since Q3 2023. Q2 EBITDA guidance of $35-55 million trailed the $70.1 million estimate, and the full-year EBITDA range was cut. Management's call for growth to reaccelerate from 4% to 18-20% looks doubtful, though revenue guidance and 30% short interest cap a short. … Show more

Hims & Hers faces mounting headwinds from an FTC lawsuit and a setback to its peptide expansion. The FTC alleges deceptive subscription practices and improper sharing of sensitive health data with ad platforms. An FDA advisory panel also voted against adding emideltide to the 503A Bulks List, a blow to Hims' peptide and compounding plans. x.com 

Hims & Hers' shift from compounded GLP-1s to branded treatments like Novo Nordisk's validates the thesis rather than hurting it, making it one of the most asymmetric buys in the market. Hims is sacrificing short-term margins to bring blockbuster weight-loss drugs onto its platform, then cross-sell higher-margin treatments. Subscribers rose 307K in Q2, partly from the Eucalyptus acquisition, and more customers bring more data, better personalization and outcomes, and more customers. x.com 

Eli Lilly has the market momentum over Novo Nordisk in GLP-1 drugs. Lilly's Zepbound sold $4B in Q1 against $2.7B for Novo's Wegovy, and Novo's lawsuit over GLP-1 advertising looks defensive. Lilly's direct-to-consumer head start and manufacturing scale appear durable. A GLP-1 market heading to $100B by 2030 remains the most structurally attractive healthcare trade. x.com